Treatment Marble Bone Disease

Osteogenesis imperfecta or brittle bone disease is a group of hereditary connective tissue disorders characterized by unusual bone fragility and tendency to fracture.

Treatment marble bone disease.

Find diagnosis treatment and prevention information on more than 20 different muscle and bone diseases and conditions affecting the musculoskeletal system. Introduction osteopetrosis is a disorder characterized by defective or absent osteoclasts the cells that resorb bone was first described in 1904 by heinrich albers schenberg. The disease progresses as long as bone growth continues. Marble bone disease rare disorder in which the bones become extremely dense hard and brittle.

Traditionally the disease has been recognized in two forms. Osteopetrosis literally stone bone also known as marble bone disease or albers schönberg disease is an extremely rare inherited disorder whereby the bones harden becoming denser in contrast to more prevalent conditions like osteoporosis in which the bones become less dense and more brittle or osteomalacia in which the bones soften. Symptoms and severity can vary greatly ranging from neonatal onset with life threatening complications such as bone marrow failure to the incidental finding of osteopetrosis on x ray depending on severity and age of onset features may include fractures. Marble this disease named for two reasons.

Osteopetrosis refers to a group of rare inherited skeletal disorders characterized by increased bone density and abnormal bone growth. The mass of bone increases but the new bone material. After all when the lumen of the opaque would be the skull spine and bones of extremities. Osteopetrosis marble bone disease osteopetrosis tarda albers schonberg disease.

The musculoskeletal system consists of the body s bones muscles tendons ligaments joints cartilage. In healthy individuals bones are constantly being broken down resorption by cells called osteoclasts and new bone material is constantly being formed by cells called osteoblasts. This means that the bone tissue is substantially sealed. Marble bone disease description causes and risk factors.

Bone marrow transplant is the only chance for survival in patients with osteopetrosis congenita. Marble bone disease when there is a failure in bone resorption. Marble bone disease causes short stature cerebral calcification and mental retardation. Osteopetrosis or marble bone disease this is an extremely rare genetic disorder of the bones in which the bones get harder and denser.

This condition in turn leads to bones getting dissolved and ultimately break. Osteogenesis imperfecta congenita which is apparent at birth and osteogenesis imperfecta tarda which manifests itself usually in early childhood with milder.